Clinical Laboratory Methods and Diagnosis
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Diagnosis of Tuberculosis: Novel Laboratory Methods
Despite advances in medical sciences in recent years, tuberculosis remains a worldwide health problem. Although there are many laboratory methods to accelerate the diagnosis, a delay in the definitive diagnosis of the disease is still a major clinical problem. Due to the slow growth of the causative agent, (Mycobacterium tuberculosis), isolation, identification, and other clinically important m...
متن کاملLaboratory diagnostic methods of malaria infection
Malaria is one of the most important tropical infectious diseases. The incidence of malaria worldwide is estimated to be 300–500 million clinical cases each year with a mortality of between one and three million people worldwide annually. The accurate and timely diagnosis of malaria infection is essential if severe complications and mortality are to be reduced by early specific antimalarial tre...
متن کاملHeparin induced thrombocytopenia
Abstract Background and Objectives Heparin is still a commonly used anticoagulant in prophylaxis and treatment of thromboembolic events. Heparin-induced thrombocytopenia (HIT) is a life-threating adverse drug reaction of heparin. The diagnosis of HIT is made based on two important criteria, firstly clinical evaluation and secondly laboratory testing. In this comprehensive review, the authors w...
متن کاملMethylmalonic Acidemia Diagnosis by Laboratory Methods
Methylmalonic acidemia (MMA) is usually caused by a deficiency of the enzyme methylmalonyl-CoA mutase (MCM), a defect in the transport or synthesis of its cofactor, adenosyl-cobalamin (cblA, cblB, cblC, cblF, cblD, and cblX), or deficiency of the enzyme methylmalonyl-CoA epimerase. A comprehensive diagnostic approach involves investigations of metabolites with tandem mass spectrometry, organic ...
متن کاملThe role of laboratory findings in the diagnosis, treatment and prognosis of bronchiolitis
Abstract Background: Acute bronchiolitis is the most common cause of lower respiratory tract infection and hospitalization due to respiratory disease during infancy. The disease is mainly diagnosed based on history and clinical examination, with paraclinical investigation being of little value in the diagnosis. The present study aimed to determine the role of paraclinical tests in the managemen...
متن کاملComparison of Two ELISA Methods for the Laboratory Diagnosis of Acute Leptospirosis
Background: Leptospirosis is the most common zoonosis widespread in tropical and temperate countries with low social-economic status. We aimed to compare an ELISA kit with an in-house ELISA assay to test the serum samples of the patients who were suspicious of leptospirosis according to their clinical symptoms. Methods: A total of 282 serum samples of patients suspicious of leptospirosis admitt...
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